Chapter 1:Microenvironmental Effects on Tumour Progression and Metastasis; Kårstein Måseide, Tuula Kalliomäki, and Richard P. Hill Chapter 2: Role of Microenvironment on Gene Expression, Angiogenesis and Microvascular Function in Tumors; Dai Fukumura Chapter 3: Imaging of Angiogenesis In Vivo with Fluorescent Proteins: Fluorescence Imaging of Angiogenesis; Robert M. Hoffman Chapter 4: The Epigenetic Influence of the Tumor Microenvironment on Melanoma Plasticity; E. A. Seftor, P.S. Meltzer, D.A. Kirschmann, R.E.B. Seftor and M. J. C. Hendrix Chapter 5: Dynamics of Cell Adhesion Interactions during Melanoma Development; G. Li and M. Herlyn Chapter 6: Matrix Metalloproteinases: Mediators of Tumour-Host Cell Interactions; Robert J. Diaz, Alexandra Eichten, Karin E. de Visser and Lisa M. Coussens Chapter 7: Role of Brain Microenvironment in Brain Metastases; J. Grunfeld and V. K. Puduvalli Chapter 8: Influence of the Bone Microenvironment on Breast Cancer Metastasis to Bone; B. L. Eckhardt, N. Pouliot and R. L. Anderson Chapter 9: Interaction of Tumour with Host Stroma in Hepatocellular Carcinoma; D.S.R. Lockwood and D.C. Gotley Chapter 10: Dynamic Nature of Tumour-Host Interactions Within the Tumor Microenvironment; D. Nagorsen and F. M. Marincola Chapter 11: Breast Cancer Progression: A \'Vicious Vycle\' of Pro-Malignancy Activities is Mediated by Inflammatory Cells, Chemokines and Cytokines; A. Ben-Baruch Chapter 12: Tumor and Host Endothelial Cell Selective Interactions and Modulation by Microenvironmental Chemokines: Tumor-Endothelial Cell Cross Talk Specificity; N. Lamerant-Fayel, C. Crola da Silva and C. Kieda Chapter 13: The Role of Chemokine Receptors, in Particular CXCR4, in Lymphoma and Carcinoma Metastasis; I. S. Zeelenberg and E.Roos Chapter 14: Energy Homeostasis and the Tumor/Host Interaction: The role of the Brain; Michael F. Wiater Chapter 15: Anti-Angiogenic and Pro-Apoptotic Effects of Dietary Restriction in Experimental Brain Cancer: Role of Glucose and Ketone Bodies; T.N. Seyfried and P. Mukherjee Chapter 16: Dietary Restriction of Specific Amino Acids Modulates Tumor and Host Interactions; G. G. Meadows and Y.-M. Fu Chapter 17: Role of Tumour Microenvironment in Chemoresistance; Yong Wei and Jessie L.-S. Au Chapter 18: Integrin-Mediated Resistance to Chemotherapy-Induced Apoptosis in Cancer Cells; R. C. Rintoul and T. Sethi Chapter 19: Bone Metastasis Microenvironment Participates in the Development of Androgen Ablation Refractoriness and Chemotherapy Resistance of Prostate Cancer Cells Residing in the Skeleton: Clinical Implications; M. Koutsilieris, R. Tenta, D. Tiblalexi, N. Pitulis, E. Sotiriou, P. Lembessis, J. Bogdanos, C. Milathianakis and A. Sourla Chapter 20: Current and Future Therapeutic Targets of the Tumour-Host Microenvironment; Jareer Kassis, Emilyn Alejandro, Victoria Virador and Elise C. Kohn Chapter 21: Bone Stromal Cells As Therapeutics Targets In Osseous Metastasis; R. A. Sikes, C. R. Cooper, G. L. Beck, F. Pruitt, M. L. Brown and G. Balian Chapter 22: Organtropism of Lung Cancer Metastasis and its Molecular Targeted Therapy; Seiji Yano, Soji Kakiuchi, Helong Zhang and Saburo Sone. Chapter 23: Maspin: A Novel Serine Protease Inhibitor; Shijie Sheng Chapter 24: Metastasis Suppressor Genes: A Brief Review of an Expanding Field; Monica M. Richert and Danny R. Welch Chapter 25: Tumor-Host Interactions at the Metastatic Site: MKK4, Signal Transduction and the Stress Response; Jonathan C. Berger, Victoria L. Robinson, Jonathan A. Hickson, Donald Vander Griend