Foreword. Schizophrenia Spectrum Disorders: Insights from views across 100 years.- 1.Negative symptoms across the schizophrenia spectrum: Phenomenological and neurobiological perspectives. -2.Neurocognitive deficits, negative symptoms, and insight in schizophrenia. -3.Stress, dissociation and schizophrenia. -4.Understanding the role of emotion in psychosis: social anxiety disorder in first-episode psychosis. -5.Face perception in schizophrenia spectrum disorders: interface between cognitive and social cognitive functioning. -6.Neuroethology of schizophrenia. -7.Quality of life deficit is a core presentation of functional psychoses. -8.Early-onset schizophrenia. -9.Prediction and early detection of first-episode psychosis. -10.Schizophrenia spectrum disorders in relation to the totality of psychosis: from first episode to long-term outcome. -11.Course of schizophrenia: What has been learned from longitudinal studies? -12.Late-onset schizophrenia: epidemiology, clinical profile, prognosis, and treatment considerations. -13.Neurological and neuropsychological endophenotypes in schizophrenia spectrum disorders. -14.The association of metacognition with neurocognition and function in schizophrenia: Advances from the study of personal narratives. -15.The relationship of acute transient psychoses and schizophrenia. -16.Schizophrenia and depression - challenging the paradigm of two separate diseases. -17.Schizo-obsessive disorder. -18.Neurophysiology of cognitive dysfunction in schizophrenia. -19.Schizophrenia spectrum disorders and risk for cancer morbidity and mortality. -Afterword. The future of the schizophrenia construct and acquisition of new knowledge.